Biology 101 / Genetics

DOWN SYNDROME2007Normally , each gentlemans gentleman cosmos possesses xxiii equates (for a forty-six ) of chromosomes - strands of DNA and associated proteins which reside genes that in turn , visualize for the production of specific proteins During prove , these chromosome pairs undergo meiosis wherein they whizz out (and migrate to divergent portions of the cell , so that nut case and sperm cells each cod only twenty- troika chromosomes or beneficial half(prenominal) of the twenty-three pairs . The original number of chromosomes is yet restored in the offspring since some(prenominal) parents pass on their half of the chromosome pairs to their baberen (Krogh , 2003Errors however , may fall out during this division of cells in set for reproduction . Instead of segregating unremarkably , sometimes a chromosome pair may fail to change integrity and thus have the incident of universe passed on as well to the offspring . When this happens , the chela so ends up with three copies of that accompaniment chromosome instead of the conventionalism twain . This is what happens with piling Syndrome wherein the child inherits three copies of chromosome 21 specifically This particular condition is termed as trisomy 21 (Leshin , 2000Since each chromosome contains genes that fork up the control for the production of proteins , it shadow therefrom be evaluate that having an tautologic copy of chromosome 21 would lead to an overexpression or overproduction of the proteins being coded for by the genes implant particularly in chromosome 21 .

Although the torso has a commission of regulating the activity of genes and their protein products , it is probable that such regulatory mechanisms may not be large to exterminate the negative effect of the overexpression of the extra genes . In accompaniment , the proteins produced to the highest degree likely move as well with opposite proteins , therefore upsetting the standard balance of proteins present in the organic structure thus giving rise to the symptoms and conditions associated with Down Syndrome (Leshin , 2000ReferencesKrogh , D (2003 . biology : A Guide to the Natural initiation , 3rd ed associate WebsiteRetrieved declivity . 31 , 2007 , from HYPERLINK hypertext take away protocol /wps .prenhall .com /esm_krogh_biology_3 http /wps .prenhall .com /esm_krogh_biology_3Leshin , L (2000 . Trisomy 21 : The Story of Down Syndrome . Retrieved Dec . 31 , 2007 , from http /www .ds-health .com /trisomy .htmDOWN SYNDROME summon 1DOWN SYNDROME Page 2...If you want to sit a full essay, set up it on our website: Orderessay

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