The cause of prostate cancer is unknown, alone several areas are being studied for practical links to the development of prostate cancer (Clinical Reference Systems, 2000). These take on heredity, a high fat diet, workplace exposure to chemicals in the rubber, metal plating and welding industries, cadmium intake, smoking cigarettes, having a vasectomy and male hormones.
Prostate cancer oft periods has no symptoms, alone when they do occur, they depend on the size of the cancer and how removed it has spread (Clinical Reference Systems, 2000). Symptoms include frequent and urgent urination, barrier urinating, blood or pus in the urine, painful urination and ejaculation, and pain in the lower back, hips and thighs.
Because there are often no symptoms associated with the early stages of prostate cancer, it is usually diagnosed at a r step to the foreine physical (Clinical Reference Systems, 2000). It can be diagnosed by a transrectal ultrasound procedure or a prostate-specific antigen (PSA) test. If each of these tests is abnormal, a biopsy is taken. Many doctors routinely do these te
Cohen, J. H., Kristal, A. R., & Stanford, J. L. (2000). Fruit and vegetable intakes and prostate cancer risk. J. Natl. crabby person Inst., 92, 61-68.
In the advanced stages of prostate cancer, suppression of androgens (AS) by any surgery or drugs controls testicular hormone secretion, and the addition of other antiandrogens such as nilutamide, flutamide, or cyproterone acetate is known as maximum androgen blockade (MAB) (Prostate crabby person Trialists, 2000). A freshen of the use of MAB to see whether or not it increases survival time in prostate cancer patients by the Prostate Cancer Trialists' Collaborative Group did not show any crucial difference between the use of AS and the use of AS combined with MAB. They also found that the studies to date did not use enough patients to really give reliable results.
Using pilfer AR-positive and AR-negative cell lines, Andriani et al (2001) used adenoviral particles containing the ARR(2)PB promoter linked to the Bax cDNA as a model for gene therapy for prostate cancer. They carried out experiments to determine if the adenovirus containing the Bax cDNA driven by the ARR(2)PB promoter can be used to overexpress the gene of interest uniquely in AR-positive prostatic epithelium. They also looked at if, in this system, overexpression of Bax is dihydrotestosterone dependent, occurs in AR-positive but androgen-independent cell lines, and is followed by apoptosis in vitro and in vivo.
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